• A2780人卵巢癌细胞(STR鉴定正确)

    价 格:¥1800

    期 货:现货(冻存管发2支)

    保藏中心:BTCC

    资源编号👨🏽‍⚖️:BTCC-1008

    产地👶🏼:中国

    套 餐:

    T25/复苏细胞 无血清冻存液 专用完全培养基500ml 南美特级胎牛血清500ml

    详细资料说明书下载质检报告(COA)

    Cell line nameA2780
    SynonymsA-2780; 2780; A2780S; A2780par
    AccessionBTCC-1008
    Resource Identification InitiativeTo cite this cell line use: A2780 (BTCC-1008)
    CommentsPart of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
    Part of: COSMIC cell lines project.
    Part of: KuDOS 95 cell line panel.
    Part of: MD Anderson Cell Lines Project.
    Part of: OCCP ovarian cancer cell line panel.
    Population: African American.
    Doubling time: 25.3 +- 1 hours (PubMed=3539322); 16 hours (PubMed=25984343); 18.41 hours (GrayJW panel).
    Microsatellite instability: Instable (MSI-low) (PubMed=15677628; Sanger).
    Omics: Array-based CGH.
    Omics: Deep exome analysis.
    Omics: Deep proteome analysis.
    Omics: Deep quantitative proteome analysis.
    Omics: DNA methylation analysis.
    Omics: Genome sequenced.
    Omics: GPI-anchored proteins analysis by proteomics.
    Omics: Metabolome analysis.
    Omics: N-glycan profiling by lectin array.
    Omics: Protein expression by reverse-phase protein arrays.
    Omics: Proteome analysis by 2D-DE/MS.
    Omics: SNP array analysis.
    Omics: Transcriptome analysis by microarray.
    Omics: Transcriptome analysis by RNAseq.
    Omics: Transcriptome analysis by serial analysis of gene expression (SAGE).
    Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
    Sequence variations
    • Mutation; HGNC; 795; ATM; Simple; p.Pro604Ser (c.1810C>T); ClinVar=VCV000127343; Zygosity=Unspecified (PubMed=25846456).
    • Mutation; HGNC; 9588; PTEN; Simple; p.Lys128_Arg130del (c.383_391del9); Zygosity=Unspecified (PubMed=25230021).
    HLA typingSource: PubMed=26589293
    Class I
    HLA-AA*26:03,26:03
    HLA-BB*37:04,49:01
    HLA-CC*02:02,07:01
    Class II
    HLA-DQDQB1*06:07,06:07
    HLA-DRDRB1*01:01,01:01
    Genome ancestrySource: PubMed=30894373

    Origin% genome


    African93.08
    Native American0
    East Asian, North2.76
    East Asian, South0
    South Asian0
    European, North0
    European, South4.17
    DiseaseOvarian endometrioid adenocarcinoma (NCIt: C7979)
    Endometrioid carcinoma of ovary (ORDO: Orphanet_454723)
    Species of originHomo sapiens (Human) (NCBI Taxonomy: 9606)
    HierarchyChildren:



    CVCL_C3NF (A2780 LIN28B KO)CVCL_C0D6 (A2780 PTX(4))CVCL_H619 (A2780-1A9)
    CVCL_ZE22 (A2780-CBDCA-R)CVCL_H745 (A2780-cisR)CVCL_EG64 (A2780-DR)
    CVCL_4T95 (A2780-DX1)CVCL_TZ68 (A2780-M)CVCL_DI16 (A2780-SCA)
    CVCL_1F93 (A2780-TC1)CVCL_7224 (A2780/100)CVCL_D156 (A2780/ACR6)
    CVCL_D157 (A2780/ACRP)CVCL_B037 (A2780/AD10)CVCL_D537 (A2780/ADDP)
    CVCL_B7S7 (A2780/C100)CVCL_F638 (A2780/C200)CVCL_F639 (A2780/C30)
    CVCL_B7S6 (A2780/C300)CVCL_B7S8 (A2780/C50)CVCL_B7S5 (A2780/C80)
    CVCL_D620 (A2780/CBP)CVCL_Y180 (A2780/cDDP)CVCL_D619 (A2780/CDDP)
    CVCL_A5AB (A2780/cmv)CVCL_A5PS (A2780/CP20)CVCL_0135 (A2780/CP70)
    CVCL_A5PT (A2780/CP8)CVCL_A5AC (A2780/m175)CVCL_A5AD (A2780/m248)
    CVCL_A5AE (A2780/m273)CVCL_4862 (A2780/R)CVCL_4863 (A2780/S)
    CVCL_IJ13 (A2780/Taxol)CVCL_4V45 (A2780/TPT)CVCL_UJ39 (A2780AD)
    CVCL_1941 (A2780ADR)CVCL_1942 (A2780cis)CVCL_UJ38 (A2780ME)
    CVCL_C1NE (A2780veliR)

    Sex of cellFemale
    Age at samplingAge unspecified
    CategoryCancer cell line
    STR profileSource(s): AddexBio; Cosmic-CLP; ECACC; ICLC; PubMed=11416159; PubMed=25230021; PubMed=25877200; PubMed=30485824

    Markers:
    AmelogeninX
    CSF1PO10,11
    D2S133821,22
    D3S135814,16
    D5S81811,12
    D7S82010
    D8S117915,17
    D13S31712,13
    D16S53911,12,13 (ICLC)
    11,13 (AddexBio; Cosmic-CLP; ECACC; PubMed=25230021; PubMed=25877200; PubMed=30485824)
    D18S5116,18
    D19S43312
    D21S1128 (PubMed=25230021; PubMed=25877200)
    28,29 (PubMed=30485824)
    FGA19,24
    Penta D8,9
    Penta E10,13
    TH016
    TPOX8,10
    vWA15,16

    Run an STR similarity search on this cell line
    Web pageshttp://dpsc.ccbr.utoronto.ca/cancer/get_cellline.pl?cellline=A2780
    https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/2/cell-lines-detail-64.html
    https://tcpaportal.org/mclp/
    https://www.phe-culturecollections.org.uk/media/113526/a2780-cell-line-profile.pdf
    Publications

    PubMed=6954533; DOI=10.1073/pnas.79.7.2194
    Westin E.H., Gallo R.C., Arya S.K., Eva A., Souza L.M., Baluda M.A., Aaronson S.A., Wong-Staal F.
    Differential expression of the amv gene in human hematopoietic cells.
    Proc. Natl. Acad. Sci. U.S.A. 79:2194-2198(1982)

    PubMed=3986765
    Louie K.G., Behrens B.C., Kinsella T.J., Hamilton T.C., Grotzinger K.R., McKoy W.M., Winker M.A., Ozols R.F.
    Radiation survival parameters of antineoplastic drug-sensitive and -resistant human ovarian cancer cell lines and their modification by buthionine sulfoximine.
    Cancer Res. 45:2110-2115(1985)

    PubMed=2429947; DOI=10.20772/cancersci1985.77.9_941
    Tsuruo T., Hamilton T.C., Louie K.G., Behrens B.C., Young R.C., Ozols R.F.
    Collateral susceptibility of adriamycin-, melphalan- and cisplatin-resistant human ovarian tumor cells to bleomycin.
    Jpn. J. Cancer Res. 77:941-945(1986)

    PubMed=3539322
    Behrens B.C., Hamilton T.C., Masuda H., Grotzinger K.R., Whang-Peng J., Louie K.G., Knutsen T., McKoy W.M., Young R.C., Ozols R.F.
    Characterization of a cis-diamminedichloroplatinum(II)-resistant human ovarian cancer cell line and its use in evaluation of platinum analogues.
    Cancer Res. 47:414-418(1987)

    PubMed=3335022
    Alley M.C., Scudiero D.A., Monks A., Hursey M.L., Czerwinski M.J., Fine D.L., Abbott B.J., Mayo J.G., Shoemaker R.H., Boyd M.R.
    Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay.
    Cancer Res. 48:589-601(1988)

    PubMed=2751261
    Mazzoni A., Trave F., Canti G., Franco P.
    Effect of the tiapamil analog RO11-2933 on cellular sensitivity to antitumor drugs in sensitive and multidrug resistant human ovarian cancer cells.
    Anticancer Res. 9:367-371(1989)

    PubMed=1999494; DOI=10.1172/JCI115080
    Parker R.J., Eastman A., Bostick-Bruton F., Reed E.
    Acquired cisplatin resistance in human ovarian cancer cells is associated with enhanced repair of cisplatin-DNA lesions and reduced drug accumulation.
    J. Clin. Invest. 87:772-777(1991)

    PubMed=1348364; DOI=10.1073/pnas.89.7.3070
    Godwin A.K., Meister A., O'Dwyer P.J., Huang C.-S., Hamilton T.C., Anderson M.E.
    High resistance to cisplatin in human ovarian cancer cell lines is associated with marked increase of glutathione synthesis.
    Proc. Natl. Acad. Sci. U.S.A. 89:3070-3074(1992)

    PubMed=8012063
    Cimoli G., Valenti M., Parodi S., Mazzoni A., De Sessa F., Conte P., Russo P.
    Reversal of 'atypical'-multidrug resistance by recombinant human tumor necrosis factor in the human ovarian cancer cell line A2780-DX3.
    Oncol. Res. 5:311-323(1993)

    PubMed=7927910; DOI=10.1002/ijc.2910590118
    Huxham I.M., Barlow A.L., Lewis A.D., Plumb J., Mairs R.J., Gaze M.N., Workman P.
    Differential intracellular processing of the anthracycline drug ME2303 in doxorubicin-sensitive (A2780) and -resistant (A2780AD) human ovarian cancer cells as studied with confocal laser scanning microscopy and image analysis.
    Int. J. Cancer 59:94-102(1994)

    PubMed=8557231; DOI=10.1006/gyno.1996.0014
    Skilling J.S., Squatrito R.C., Connor J.P., Niemann T., Buller R.E.
    p53 gene mutation analysis and antisense-mediated growth inhibition of human ovarian carcinoma cell lines.
    Gynecol. Oncol. 60:72-80(1996)

    PubMed=9041185
    Johnson S.W., Laub P.B., Beesley J.S., Ozols R.F., Hamilton T.C.
    Increased platinum-DNA damage tolerance is associated with cisplatin resistance and cross-resistance to various chemotherapeutic agents in unrelated human ovarian cancer cell lines.
    Cancer Res. 57:850-856(1997)

    PubMed=11103784
    Hough C.D., Sherman-Baust C.A., Pizer E.S., Montz F.J., Im D.D., Rosenshein N.B., Cho K.R., Riggins G.J., Morin P.J.
    Large-scale serial analysis of gene expression reveals genes differentially expressed in ovarian cancer.
    Cancer Res. 60:6281-6287(2000)

    PubMed=12080474; DOI=10.1038/sj.onc.1205542
    Manzano R.G., Montuenga L.M., Dayton M., Dent P., Kinoshita I., Vicent S., Gardner G.J., Nguyen P., Choi Y.-H., Trepel J., Auersperg N., Birrer M.J.
    CL100 expression is down-regulated in advanced epithelial ovarian cancer and its re-expression decreases its malignant potential.
    Oncogene 21:4435-4447(2002)

    PubMed=15677628; DOI=10.1093/carcin/bgi032
    Gorringe K.L., Chin S.-F., Pharoah P.D.P., Staines J.M., Oliveira C., Edwards P.A.W., Caldas C.
    Evidence that both genetic instability and selection contribute to the accumulation of chromosome alterations in cancer.
    Carcinogenesis 26:923-930(2005)

    PubMed=18273836; DOI=10.1002/gcc.20547
    Prasad M., Bernardini M., Tsalenko A., Marrano P., Paderova J., Lee C.H., Ben-Dor A., Barrett M.T., Squire J.A.
    High definition cytogenetics and oligonucleotide aCGH analyses of cisplatin-resistant ovarian cancer cells.
    Genes Chromosomes Cancer 47:427-436(2008)

    PubMed=19714814; DOI=10.1021/pr800856b
    Cicchillitti L., Di Michele M., Urbani A., Ferlini C., Donat M.B., Scambia G., Rotilio D.
    Comparative proteomic analysis of paclitaxel sensitive A2780 epithelial ovarian cancer cell line and its resistant counterpart A2780TC1 by 2D-DIGE: the role of ERp57.
    J. Proteome Res. 8:1902-1912(2009)

    PubMed=20164919; DOI=10.1038/nature08768
    Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.
    Signatures of mutation and selection in the cancer genome.
    Nature 463:893-898(2010)

    PubMed=20204287; DOI=10.3892/or_00000728
    Langland G.T., Yannone S.M., Langland R.A., Nakao A., Guan Y.-H., Long S.B.T., Vonguyen L., Chen D.J., Gray J.W., Chen F.-Q.
    Radiosensitivity profiles from a panel of ovarian cancer cell lines exhibiting genetic alterations in p53 and disparate DNA-dependent protein kinase activities.
    Oncol. Rep. 23:1021-1026(2010)

    PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
    Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
    A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
    Cancer Res. 70:2158-2164(2010)

    PubMed=22328975; DOI=10.1158/2159-8290.CD-11-0170
    Hanrahan A.J., Schultz N., Westfal M.L., Sakr R.A., Giri D.D., Scarperi S., Janakiraman M., Olvera N., Stevens E.V., She Q.-B., Aghajanian C., King T.A., de Stanchina E., Spriggs D.R., Heguy A., Taylor B.S., Sander C., Rosen N., Levine D.A., Solit D.B.
    Genomic complexity and AKT dependence in serous ovarian cancer.
    Cancer Discov. 2:56-67(2012)

    PubMed=22460905; DOI=10.1038/nature11003
    Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.-Y.K., Yu J.-J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N.-X., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M.L., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
    The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
    Nature 483:603-607(2012)

    PubMed=22585861; DOI=10.1158/2159-8290.CD-11-0224
    Marcotte R., Brown K.R., Suarez Saiz F.J., Sayad A., Karamboulas K., Krzyzanowski P.M., Sircoulomb F., Medrano M., Fedyshyn Y., Koh J.L.Y., van Dyk D., Fedyshyn B., Luhova M., Brito G.C., Vizeacoumar F.J., Vizeacoumar F.S., Datti A., Kasimer D., Buzina A., Mero P., Misquitta C., Normand J., Haider M., Ketela T., Wrana J.L., Rottapel R., Neel B.G., Moffat J.
    Essential gene profiles in breast, pancreatic, and ovarian cancer cells.
    Cancer Discov. 2:172-189(2012)

    PubMed=22705003; DOI=10.1016/j.humpath.2012.03.011
    Rahman M., Nakayama K., Rahman M.T., Nakayama N., Ishikawa M., Katagiri A., Iida K., Nakayama S., Otsuki Y., Shih I.-M., Miyazaki K.
    Clinicopathologic and biological analysis of PIK3CA mutation in ovarian clear cell carcinoma.
    Hum. Pathol. 43:2197-2206(2012)

    PubMed=22710073; DOI=10.1016/j.ygyno.2012.06.017
    Korch C.T., Spillman M.A., Jackson T.A., Jacobsen B.M., Murphy S.K., Lessey B.A., Jordan V.C., Bradford A.P.
    DNA profiling analysis of endometrial and ovarian cell lines reveals misidentification, redundancy and contamination.
    Gynecol. Oncol. 127:241-248(2012)

    PubMed=23415752; DOI=10.1016/j.molonc.2012.12.007
    Stordal B., Timms K., Farrelly A., Gallagher D., Busschots S., Renaud M., Thery J., Williams D., Potter J., Tran T., Korpanty G., Cremona M., Carey M.S., Li J., Li Y., Aslan O., O'Leary J.J., Mills G.B., Hennessy B.T.
    BRCA1/2 mutation analysis in 41 ovarian cell lines reveals only one functionally deleterious BRCA1 mutation.
    Mol. Oncol. 7:567-579(2013)

    PubMed=23839242; DOI=10.1038/ncomms3126
    Domcke S., Sinha R., Levine D.A., Sander C., Schultz N.
    Evaluating cell lines as tumour models by comparison of genomic profiles.
    Nat. Commun. 4:2126.1-2126.10(2013)

    PubMed=24023729; DOI=10.1371/journal.pone.0072162
    Anglesio M.S., Wiegand K.C., Melnyk N., Chow C., Salamanca C.M., Prentice L.M., Senz J., Yang W., Spillman M.A., Cochrane D.R., Shumansky K., Shah S.P., Kalloger S.E., Huntsman D.G.
    Type-specific cell line models for type-specific ovarian cancer research.
    PLoS ONE 8:E72162-E72162(2013)

    PubMed=25230021; DOI=10.1371/journal.pone.0103988
    Beaufort C.M., Helmijr J.C.A., Piskorz A.M., Hoogstraat M., Ruigrok-Ritstier K., Besselink N., Murtaza M., van IJcken W.F.J., Heine A.A.J., Smid M., Koudijs M.J., Brenton J.D., Berns E.M.J.J., Helleman J.
    Ovarian cancer cell line panel (OCCP): clinical importance of in vitro morphological subtypes.
    PLoS ONE 9:E103988-E103988(2014)

    PubMed=25984343; DOI=10.1038/sdata.2014.35
    Cowley G.S., Weir B.A., Vazquez F., Tamayo P., Scott J.A., Rusin S., East-Seletsky A., Ali L.D., Gerath W.F.J., Pantel S.E., Lizotte P.H., Jiang G.-Z., Hsiao J., Tsherniak A., Dwinell E., Aoyama S., Okamoto M., Harrington W., Gelfand E.T., Green T.M., Tomko M.J., Gopal S., Wong T.C., Li H.-B., Howell S., Stransky N., Liefeld T., Jang D., Bistline J., Meyers B.H., Armstrong S.A., Anderson K.C., Stegmaier K., Reich M., Pellman D., Boehm J.S., Mesirov J.P., Golub T.R., Root D.E., Hahn W.C.
    Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.
    Sci. Data 1:140035-140035(2014)

    PubMed=25485619; DOI=10.1038/nbt.3080
    Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z.-S., Liu H.-B., Degenhardt J., Mayba O., Gnad F., Liu J.-F., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M.-M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.-M.
    A comprehensive transcriptional portrait of human cancer cell lines.
    Nat. Biotechnol. 33:306-312(2015)

    PubMed=25846456; DOI=10.3892/ijo.2015.2951
    Takenaka M., Saito M., Iwakawa R., Yanaihara N., Saito M., Kato M., Ichikawa H., Shibata T., Yokota J., Okamoto A., Kohno T.
    Profiling of actionable gene alterations in ovarian cancer by targeted deep sequencing.
    Int. J. Oncol. 46:2389-2398(2015)

    PubMed=26589293; DOI=10.1186/s13073-015-0240-5
    Scholtalbers J., Boegel S., Bukur T., Byl M., Goerges S., Sorn P., Loewer M., Sahin U., Castle J.C.
    TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
    Genome Med. 7:118.1-118.7(2015)

    PubMed=26972028; DOI=10.1016/j.jprot.2016.03.008
    Masuishi Y., Kimura Y., Arakawa N., Hirano H.
    Identification of glycosylphosphatidylinositol-anchored proteins and omega-sites using TiO2-based affinity purification followed by hydrogen fluoride treatment.
    J. Proteomics 139:77-83(2016)

    PubMed=27141528; DOI=10.1016/j.dib.2016.04.001
    Masuishi Y., Kimura Y., Arakawa N., Hirano H.
    Data for identification of GPI-anchored peptides and omega-sites in cancer cell lines.
    Data Brief 7:1302-1305(2016)

    PubMed=27235858; DOI=10.1016/j.ygyno.2016.05.028
    Hernandez L., Kim M.K., Lyle L.T., Bunch K.P., House C.D., Ning F., Noonan A.M., Annunziata C.M.
    Characterization of ovarian cancer cell lines as in vivo models for preclinical studies.
    Gynecol. Oncol. 142:332-340(2016)

    PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
    Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X.-M., Egan R.K., Liu Q.-S., Mironenko T., Mitropoulos X., Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
    A landscape of pharmacogenomic interactions in cancer.
    Cell 166:740-754(2016)

    PubMed=27561551; DOI=10.1038/ncomms12645
    Coscia F., Watters K.M., Curtis M., Eckert M.A., Chiang C.Y., Tyanova S., Montag A., Lastra R.R., Lengyel E., Mann M.
    Integrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status.
    Nat. Commun. 7:12645.1-12645.14(2016)

    PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
    Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P., Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B., Liang H.
    Characterization of human cancer cell lines by reverse-phase protein arrays.
    Cancer Cell 31:225-239(2017)

    PubMed=28273451; DOI=10.1016/j.celrep.2017.02.028
    Medrano M., Communal L., Brown K.R., Iwanicki M., Normand J., Paterson J., Sircoulomb F., Krzyzanowski P.M., Novak M., Doodnauth S.A., Suarez Saiz F.J., Cullis J., Al-Awar R., Neel B.G., McPherson J., Drapkin R.I., Ailles L., Mes-Masson A.-M., Rottapel R.
    Interrogation of functional cell-surface markers identifies CD151 dependency in high-grade serous ovarian cancer.
    Cell Rep. 18:2343-2358(2017)

    PubMed=28546799; DOI=10.1186/s12014-017-9155-z
    Zhao R., Qin W.-J., Qin R.-H., Han J., Li C., Wang Y.-S., Xu C.-J.
    Lectin array and glycogene expression analyses of ovarian cancer cell line A2780 and its cisplatin-resistant derivate cell line A2780-cp.
    Clin. Proteomics 14:20.1-20.10(2017)

    PubMed=30485824; DOI=10.1016/j.celrep.2018.10.096
    Papp E., Hallberg D., Konecny G.E., Bruhm D.C., Adleff V., Noe M., Kagiampakis I., Palsgrove D., Conklin D., Kinose Y., White J.R., Press M.F., Drapkin R.I., Easwaran H., Baylin S.B., Slamon D.J., Velculescu V.E., Scharpf R.B.
    Integrated genomic, epigenomic, and expression analyses of ovarian cancer cell lines.
    Cell Rep. 25:2617-2633(2018)

    PubMed=30894224; DOI=10.1186/s40659-019-0220-0
    Viscarra T., Buchegger K., Jofre I.A., Riquelme I., Zanella L., Abanto Marin M., Parker A.C., Piccolo S.R., Roa J.C., Ili C.G., Brebi P.
    Functional and transcriptomic characterization of carboplatin-resistant A2780 ovarian cancer cell line.
    Biol. Res. 52:13.1-13.13(2019)

    PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
    Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
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    Cancer Res. 79:1263-1273(2019)

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    Next-generation characterization of the Cancer Cell Line Encyclopedia.
    Nature 569:503-508(2019)

    PubMed=31978347; DOI=10.1016/j.cell.2019.12.023
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    Quantitative proteomics of the Cancer Cell Line Encyclopedia.
    Cell 180:387-402.e16(2020)

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    Cross-references
    Cell line databases/resourcesCLO; CLO_0001571
    MCCL; MCC:0000027
    CLDB; cl193
    CLDB; cl194
    CLDB; cl4894
    Cell_Model_Passport; SIDM00210
    Cosmic-CLP; 906804
    DepMap; ACH-000657
    LINCS_LDP; LCL-1518
    Lonza; 207
    Anatomy/cell type resourcesBTO; BTO:0002549
    Biological sample resourcesBioSample; SAMN03472806
    BioSample; SAMN10988216
    Cell line collections (Providers)AddexBio; C0017002/20
    BCRJ; 0031
    CancerTools; 152706
    ECACC; 93112519
    ICLC; HTL98008
    NCI-DTP; A2780
    Ximbio; 152706
    Chemistry resourcesChEMBL-Cells; CHEMBL3308421
    ChEMBL-Targets; CHEMBL614004
    GDSC; 906804
    PharmacoDB; A2780_40_2019
    PubChem_Cell_line; CVCL_0134
    Encyclopedic resourcesWikidata; Q54606559
    Experimental variables resourcesEFO; EFO_0006362
    Gene expression databasesArrayExpress; E-MTAB-783
    ArrayExpress; E-MTAB-2706
    ArrayExpress; E-MTAB-2770
    ArrayExpress; E-MTAB-3610
    GEO; GSM184388
    GEO; GSM184389
    GEO; GSM383925
    GEO; GSM503257
    GEO; GSM659370
    GEO; GSM711722
    GEO; GSM827312
    GEO; GSM851909
    GEO; GSM886853
    GEO; GSM887918
    GEO; GSM1001419
    GEO; GSM1001420
    GEO; GSM1001488
    GEO; GSM1291126
    GEO; GSM1291129
    GEO; GSM1340577
    GEO; GSM1374380
    GEO; GSM1374381
    GEO; GSM1669581
    GEO; GSM2474971
    GEO; GSM4845007
    GEO; GSM4845008
    Metabolomic databasesMetaboLights; MTBLS156
    MetaboLights; MTBLS1014
    Polymorphism and mutation databasesCosmic; 688090
    Cosmic; 755844
    Cosmic; 849607
    Cosmic; 906804
    Cosmic; 923108
    Cosmic; 948284
    Cosmic; 987394
    Cosmic; 1093558
    Cosmic; 1102819
    Cosmic; 1139223
    Cosmic; 1198265
    Cosmic; 1305309
    Cosmic; 1609529
    Cosmic; 1707564
    Cosmic; 1708387
    Cosmic; 1709251
    Cosmic; 1945872
    Cosmic; 1995331
    Cosmic; 2582805
    Cosmic; 2674698
    IARC_TP53; 21161
    LiGeA; CCLE_809
    Progenetix; CVCL_0134
    Proteomic databasesPRIDE; PXD001176
    PRIDE; PXD003105
    PRIDE; PXD003252
    PRIDE; PXD003668
    PRIDE; PXD013811
    PRIDE; PXD030304
    Sequence databasesEGA; EGAS00001000610
    EGA; EGAS00001000978
    Entry history
    Entry creation04-Apr-2012
    Last entry update29-Jun-2023
    Version number43

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