• SNU216人胃癌细胞

    价 格🧑🏻‍🦲:¥1800

    期 货🆖:现货(冻存管发2支)

    保藏中心🌭:BTCC

    资源编号:BTCC-1319

    产地:中国

    套 餐🏌🏿:

    T25/复苏细胞 无血清冻存液 专用完全培养基500ml 南美特级胎牛血清500ml

    详细资料说明书下载质检报告(COA)

    Cell line nameSNU-216
    SynonymsSNU216; NCI-SNU-216
    AccessionBTCC-1319
    Resource Identification InitiativeTo cite this cell line use: SNU-216 (BTCC-1319)
    CommentsPart of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
    Part of: Seoul National University (SNU) cell line collection.
    Population: Korean.
    Omics: Deep exome analysis.
    Omics: SNP array analysis.
    Omics: Transcriptome analysis by microarray.
    Omics: Transcriptome analysis by RNAseq.
    Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027.
    Sequence variations
    • Mutation; HGNC; 11998; TP53; Simple; p.Val216Met (c.646G>A); ClinVar=VCV000182965; Zygosity=Homozygous (PubMed=9033653; DepMap).
    HLA typingSource: PubMed=25960936
    Class I
    HLA-AA*24:02,24:02
    HLA-BB*51:01,52:01
    HLA-CC*12:02,12:02
    Class II
    HLA-DRDRB1*15:02,15:02

    Source: PubMed=26589293
    Class I
    HLA-AA*24:02,24:02
    HLA-BB*52:01,52:01
    HLA-CC*12:02,12:02
    Genome ancestrySource: PubMed=30894373

    Origin% genome


    African2.54
    Native American0
    East Asian, North69.93
    East Asian, South26.25
    South Asian0
    European, North0
    European, South1.27
    DiseaseGastric tubular adenocarcinoma (NCIt: C5473)
    Species of originHomo sapiens (Human) (NCBI Taxonomy: 9606)
    Sex of cellFemale
    Age at sampling46Y
    CategoryCancer cell line
    STR profileSource(s): KCLB; PubMed=25877200

    Markers:
    AmelogeninX
    CSF1PO12
    D3S135817
    D5S81811
    D7S8208,10
    D8S117913,16
    D13S3179
    D16S53910,13
    D18S5116
    D21S1130,33.2
    FGA21
    Penta D9,13
    Penta E5
    TH017
    TPOX9
    vWA14,20

    Run an STR similarity search on this cell line
    Publications

    PubMed=9033653; DOI=10.1002/(SICI)1097-0215(19970207)70:4<443::aid-ijc12>3.0.CO;2-G
    Park J.-G., Yang H.-K., Kim W.-H., Chung J.-K., Kang M.-S., Lee J.-H., Oh J.-H., Park H.-S., Yeo K.-S., Kang S.H., Song S.-Y., Kang Y.K., Bang Y.-J., Kim Y.I., Kim J.-P.
    Establishment and characterization of human gastric carcinoma cell lines.
    Int. J. Cancer 70:443-449(1997)

    PubMed=15723654; DOI=10.1111/j.1349-7006.2005.00016.x
    Takada H., Imoto I., Tsuda H., Sonoda I., Ichikura T., Mochizuki H., Okanoue T., Inazawa J.
    Screening of DNA copy-number aberrations in gastric cancer cell lines by array-based comparative genomic hybridization.
    Cancer Sci. 96:100-110(2005)

    PubMed=19956504; DOI=10.4143/crt.2005.37.1.1
    Ku J.-L., Park J.-G.
    Biology of SNU cell lines.
    Cancer Res. Treat. 37:1-19(2005)

    PubMed=22460905; DOI=10.1038/nature11003
    Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.-Y.K., Yu J.-J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N.-X., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M.L., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
    The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
    Nature 483:603-607(2012)

    PubMed=24807215; DOI=10.1038/ncomms4830
    Liu J.-F., McCleland M.L., Stawiski E.W., Gnad F., Mayba O., Haverty P.M., Durinck S., Chen Y.-J., Klijn C., Jhunjhunwala S., Lawrence M., Liu H.-B., Wan Y.-N., Chopra V.S., Yaylaoglu M.B., Yuan W.-L., Ha C., Gilbert H.N., Reeder J., Pau G., Stinson J., Stern H.M., Manning G., Wu T.D., Neve R.M., de Sauvage F.J., Modrusan Z., Seshagiri S., Firestein R., Zhang Z.-M.
    Integrated exome and transcriptome sequencing reveals ZAK isoform usage in gastric cancer.
    Nat. Commun. 5:3830.1-3830.8(2014)

    PubMed=25960936; DOI=10.4161/21624011.2014.954893
    Boegel S., Lower M., Bukur T., Sahin U., Castle J.C.
    A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines.
    OncoImmunology 3:e954893.1-e954893.12(2014)

    PubMed=25485619; DOI=10.1038/nbt.3080
    Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z.-S., Liu H.-B., Degenhardt J., Mayba O., Gnad F., Liu J.-F., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M.-M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.-M.
    A comprehensive transcriptional portrait of human cancer cell lines.
    Nat. Biotechnol. 33:306-312(2015)

    PubMed=26589293; DOI=10.1186/s13073-015-0240-5
    Scholtalbers J., Boegel S., Bukur T., Byl M., Goerges S., Sorn P., Loewer M., Sahin U., Castle J.C.
    TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
    Genome Med. 7:118.1-118.7(2015)

    PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
    Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
    An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
    Cancer Res. 79:1263-1273(2019)

    PubMed=31068700; DOI=10.1038/s41586-019-1186-3
    Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J.G., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
    Next-generation characterization of the Cancer Cell Line Encyclopedia.
    Nature 569:503-508(2019)

    Cross-references
    Cell line databases/resourcesCell_Model_Passport; SIDM01393
    CGH-DB; 124-1
    CGH-DB; 9012-4
    DepMap; ACH-000466
    Anatomy/cell type resourcesBTO; BTO:0004988
    Biological sample resourcesBioSample; SAMN03473182
    BioSample; SAMN10988071
    Cell line collections (Providers)KCLB; 00216
    Chemistry resourcesPharmacoDB; SNU216_1451_2019
    Encyclopedic resourcesWikidata; Q54955148
    Experimental variables resourcesEFO; EFO_0006754

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