• OE33人食管癌细胞(STR鉴定正确)

    价 格:¥1800

    期 货:现货(冻存管发2支)

    保藏中心:BTCC

    资源编号:BTCC-1277

    产地:中国

    套 餐🦸🏻:

    T25/复苏细胞 无血清冻存液 专用完全培养基500ml 南美特级胎牛血清500ml

    详细资料说明书下载质检报告(COA)

    Cell line nameOE33
    SynonymsOE-33; JROECL 33; JROECL33; OEC33
    AccessionBTCC-1277
    Resource Identification InitiativeTo cite this cell line use: OE33 (BTCC-1277)
    CommentsPart of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
    Part of: COSMIC cell lines project.
    Part of: MD Anderson Cell Lines Project.
    Part of: TCGA-110-CL cell line panel.
    Population: Caucasian.
    Doubling time: 33 hours (PubMed=25984343); ~30 hours (DSMZ=ACC-706).
    Microsatellite instability: Stable (MSS) (Sanger).
    Omics: Chromatin accessibility by ATAC-seq.
    Omics: Deep exome analysis.
    Omics: Deep quantitative proteome analysis.
    Omics: DNA methylation analysis.
    Omics: Genome sequenced.
    Omics: Hi-C chromosome conformation analysis.
    Omics: Protein expression by reverse-phase protein arrays.
    Omics: shRNA library screening.
    Omics: SNP array analysis.
    Omics: Transcriptome analysis by microarray.
    Omics: Transcriptome analysis by RNAseq.
    Derived from site: In situ; Esophagus; UBERON=UBERON_0001043.
    Sequence variations
    HLA typingSource: PubMed=26589293
    Class I
    HLA-AA*01:01,01:01
    HLA-BB*08:01,08:01
    HLA-CC*07:06,07:06
    Genome ancestrySource: PubMed=30894373

    Origin% genome


    African0.01
    Native American0
    East Asian, North1.2
    East Asian, South0.55
    South Asian0
    European, North67.21
    European, South31.03
    DiseaseBarrett adenocarcinoma (NCIt: C7027)
    Adenocarcinoma of the esophagus (ORDO: Orphanet_99976)
    Species of originHomo sapiens (Human) (NCBI Taxonomy: 9606)
    Sex of cellFemale
    Age at sampling73Y
    CategoryCancer cell line
    STR profileSource(s): Cosmic-CLP; DSMZ; ECACC; PubMed=20075370; PubMed=25877200

    Markers:
    AmelogeninX
    CSF1PO10 (ECACC; PubMed=25877200)
    10,11 (Cosmic-CLP; DSMZ; PubMed=20075370)
    D2S133817,19,20 (PubMed=25877200)
    17,20 (DSMZ)
    D3S135818
    D5S81811
    D7S8209,10
    D8S117910,11,12 (DSMZ; PubMed=20075370)
    10,12 (PubMed=25877200)
    D13S31714
    D16S53912
    D18S5112
    D19S43312,15,16
    D21S1129,31.2
    FGA23
    Penta D8,9,11 (DSMZ)
    9,11 (PubMed=25877200)
    Penta E12,18
    TH017 (DSMZ)
    7,8 (Cosmic-CLP; ECACC; PubMed=20075370; PubMed=25877200)
    TPOX8,11
    vWA14,17 (PubMed=25877200)
    17 (Cosmic-CLP; DSMZ; ECACC; PubMed=20075370)

    Run an STR similarity search on this cell line
    Web pageshttps://tcpaportal.org/mclp/
    Publications

    PubMed=9010035; DOI=10.1038/bjc.1997.42
    Rockett J.C., Larkin K., Darnton S.J., Morris A.G., Matthews H.R.
    Five newly established oesophageal carcinoma cell lines: phenotypic and immunological characterization.
    Br. J. Cancer 75:258-263(1997)

    PubMed=11520067; DOI=10.1006/bbrc.2001.5400
    Kan T., Shimada Y., Sato F., Maeda M., Kawabe A., Kaganoi J.-I., Itami A., Yamasaki S., Imamura M.
    Gene expression profiling in human esophageal cancers using cDNA microarray.
    Biochem. Biophys. Res. Commun. 286:792-801(2001)

    PubMed=20075370; DOI=10.1093/jnci/djp499
    Boonstra J.J., van Marion R., Beer D.G., Lin L., Chaves P., Ribeiro C., Pereira A.D., Roque L., Darnton S.J., Altorki N.K., Schrump D.S., Klimstra D.S., Tang L.H., Eshleman J.R., Alvarez H., Shimada Y., van Dekken H., Tilanus H.W., Dinjens W.N.M.
    Verification and unmasking of widely used human esophageal adenocarcinoma cell lines.
    J. Natl. Cancer Inst. 102:271-274(2010)

    PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
    Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
    A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
    Cancer Res. 70:2158-2164(2010)

    PubMed=22460905; DOI=10.1038/nature11003
    Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.-Y.K., Yu J.-J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N.-X., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M.L., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
    The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
    Nature 483:603-607(2012)

    PubMed=25984343; DOI=10.1038/sdata.2014.35
    Cowley G.S., Weir B.A., Vazquez F., Tamayo P., Scott J.A., Rusin S., East-Seletsky A., Ali L.D., Gerath W.F.J., Pantel S.E., Lizotte P.H., Jiang G.-Z., Hsiao J., Tsherniak A., Dwinell E., Aoyama S., Okamoto M., Harrington W., Gelfand E.T., Green T.M., Tomko M.J., Gopal S., Wong T.C., Li H.-B., Howell S., Stransky N., Liefeld T., Jang D., Bistline J., Meyers B.H., Armstrong S.A., Anderson K.C., Stegmaier K., Reich M., Pellman D., Boehm J.S., Mesirov J.P., Golub T.R., Root D.E., Hahn W.C.
    Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.
    Sci. Data 1:140035-140035(2014)

    PubMed=23795680; DOI=10.1111/dote.12095
    Boonstra J.J., Tilanus H.W., Dinjens W.N.M.
    Translational research on esophageal adenocarcinoma: from cell line to clinic.
    Dis. Esophagus 28:90-96(2015)

    PubMed=26512696; DOI=10.3390/cancers7040881
    O'Callaghan C., Fanning L.J., Barry O.P.
    Hypermethylation of MAPK13 promoter in oesophageal squamous cell carcinoma is associated with loss of p38delta MAPK expression.
    Cancers (Basel) 7:2124-2133(2015)

    PubMed=26589293; DOI=10.1186/s13073-015-0240-5
    Scholtalbers J., Boegel S., Bukur T., Byl M., Goerges S., Sorn P., Loewer M., Sahin U., Castle J.C.
    TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
    Genome Med. 7:118.1-118.7(2015)

    PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
    Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X.-M., Egan R.K., Liu Q.-S., Mironenko T., Mitropoulos X., Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
    A landscape of pharmacogenomic interactions in cancer.
    Cell 166:740-754(2016)

    PubMed=27594985; DOI=10.12688/f1000research.7033.1
    Contino G., Eldridge M.D., Secrier M., Bower L., Elliott R.F., Weaver J., Lynch A.G., Edwards P.A.W., Fitzgerald R.C.
    Whole-genome sequencing of nine esophageal adenocarcinoma cell lines.
    F1000Research 5:1336.1-1336.12(2016)

    PubMed=27600491; DOI=10.1038/srep32417
    Garcia E., Hayden A., Birts C., Britton E., Cowie A., Pickard K., Mellone M., Choh C.T.P., Derouet M.F., Duriez P., Noble F., White M.J., Primrose J.N., Strefford J.C., Rose-Zerilli M.J., Thomas G.J., Ang Y.S., Sharrocks A.D., Fitzgerald R.C., Underwood T.J.
    Authentication and characterisation of a new oesophageal adenocarcinoma cell line: MFD-1.
    Sci. Rep. 6:32417-32417(2016)

    PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
    Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P., Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B., Liang H.
    Characterization of human cancer cell lines by reverse-phase protein arrays.
    Cancer Cell 31:225-239(2017)

    PubMed=28504813; DOI=10.3892/or.2017.5640
    Melsens E., De Vlieghere E., Descamps B., Vanhove C., De Wever O., Ceelen W., Pattyn P.
    Improved xenograft efficiency of esophageal adenocarcinoma cell lines through in vivo selection.
    Oncol. Rep. 38:71-81(2017)

    PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
    Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
    An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
    Cancer Res. 79:1263-1273(2019)

    PubMed=31068700; DOI=10.1038/s41586-019-1186-3
    Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J.G., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
    Next-generation characterization of the Cancer Cell Line Encyclopedia.
    Nature 569:503-508(2019)

    PubMed=31395879; DOI=10.1038/s41467-019-11415-2
    Yu K., Chen B., Aran D., Charalel J., Yau C., Wolf D.M., van 't Veer L.J., Butte A.J., Goldstein T., Sirota M.
    Comprehensive transcriptomic analysis of cell lines as models of primary tumors across 22 tumor types.
    Nat. Commun. 10:3574.1-3574.11(2019)

    PubMed=31978347; DOI=10.1016/j.cell.2019.12.023
    Nusinow D.P., Szpyt J., Ghandi M., Rose C.M., McDonald E.R. III, Kalocsay M., Jane-Valbuena J., Gelfand E.T., Schweppe D.K., Jedrychowski M.P., Golji J., Porter D.A., Rejtar T., Wang Y.K., Kryukov G.V., Stegmeier F., Erickson B.K., Garraway L.A., Sellers W.R., Gygi S.P.
    Quantitative proteomics of the Cancer Cell Line Encyclopedia.
    Cell 180:387-402.e16(2020)

    PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010
    Goncalves E., Poulos R.C., Cai Z.-X., Barthorpe S., Manda S.S., Lucas N., Beck A., Bucio-Noble D., Dausmann M., Hall C., Hecker M., Koh J., Lightfoot H., Mahboob S., Mali I., Morris J., Richardson L., Seneviratne A.J., Shepherd R., Sykes E., Thomas F., Valentini S., Williams S.G., Wu Y.-X., Xavier D., MacKenzie K.L., Hains P.G., Tully B., Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.
    Pan-cancer proteomic map of 949 human cell lines.
    Cancer Cell 40:835-849.e8(2022)

    Cross-references
    Cell line databases/resourcesCLO; CLO_0008240
    MCCL; MCC:0000369
    CLDB; cl3762
    Cell_Model_Passport; SIDM00477
    Cosmic-CLP; 910549
    DepMap; ACH-000383
    DSMZCellDive; ACC-706
    IGRhCellID; OE33
    LINCS_LDP; LCL-1797
    Anatomy/cell type resourcesBTO; BTO:0003541
    Biological sample resourcesBioSample; SAMN03472890
    BioSample; SAMN03473392
    BioSample; SAMN10987775
    Cell line collections (Providers)AddexBio; C0013003/115
    AddexBio; C0013004/121
    DSMZ; ACC-706
    ECACC; 96070808
    Chemistry resourcesChEMBL-Cells; CHEMBL3308776
    ChEMBL-Targets; CHEMBL1075556
    GDSC; 910549
    PharmacoDB; OE33_1196_2019
    PubChem_Cell_line; CVCL_0471
    Encyclopedic resourcesWikidata; Q54931865
    Experimental variables resourcesEFO; EFO_0002310

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