• SGC-7901人胃癌细胞(STR鉴定为HELA)

    价 格🧑🏼‍🔬:¥1800

    期 货🤳🏿:现货(冻存管发2支)

    保藏中心:BTCC

    资源编号:BTCC-1157

    产地:中国

    套 餐:

    T25/复苏细胞 无血清冻存液 专用完全培养基500ml 南美特级胎牛血清500ml

    详细资料说明书下载质检报告(COA)

    Cell line nameSGC-7901
    SynonymsSGC 7901; SGC7901
    AccessionBTCC-1157
    Resource Identification InitiativeTo cite this cell line use: SGC-7901 (BTCC-1157)
    CommentsProblematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=26116706; PubMed=28851942). Originally thought to originate from the lymph node of a 56 year old female patient with a gastric carcinoma.
    Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00577.
    Population: African American.
    Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
    Omics: Proteome analysis by 2D-DE/MS.
    Omics: Transcriptome analysis by microarray.
    Miscellaneous: Formerly the CCRID database had 2 entries describing this cell line (3111C0001CCC000236, 3131C0001000700046). They were one of the sources for the STR profile of this entry.
    Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
    DiseaseHuman papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
    Species of originHomo sapiens (Human) (NCBI Taxonomy: 9606)
    HierarchyParent: CVCL_0030 (HeLa)
    Children:



    CVCL_RK37 (SGC-7901/B1)CVCL_RK36 (SGC-7901/B2)CVCL_VU57 (SGC7901/ADR)
    CVCL_B0A1 (SGC7901/OXA)CVCL_VU58 (SGC7901/VCR)
    Sex of cellFemale
    Age at sampling30Y6M
    CategoryCancer cell line
    STR profileSource(s): CCRID; PubMed=26116706; PubMed=28851942; PubMed=29717028

    Markers:
    AmelogeninX
    CSF1PO9,10 (PubMed=26116706; PubMed=29717028)
    10 (CCRID; PubMed=28851942)
    D2S133817
    D3S135815,18 (CCRID; PubMed=26116706; PubMed=29717028)
    16,18 (PubMed=28851942)
    D5S81811,12
    D6S104318,19
    D7S8208,12 (PubMed=26116706; PubMed=29717028)
    12 (CCRID; PubMed=28851942)
    D8S117912 (CCRID; PubMed=28851942)
    12,13 (PubMed=26116706; PubMed=29717028)
    D12S39120,25
    D13S31712,13.3 (PubMed=26116706; PubMed=29717028)
    13.3 (CCRID; PubMed=28851942)
    D16S5399,10
    D18S5116
    D19S43313 (CCRID; PubMed=28851942)
    13,14 (PubMed=26116706; PubMed=29717028)
    D21S1127,28
    FGA18,21 (CCRID; PubMed=28851942)
    21 (PubMed=26116706; PubMed=29717028)
    Penta D8,15
    Penta E7,17
    TH017
    TPOX8,12 (PubMed=26116706; PubMed=29717028)
    12 (CCRID; PubMed=28851942)
    vWA16,18

    Run an STR similarity search on this cell line
    Web pageshttps://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx
    Publications

    DOI=10.1360/sb1982-27-12-1355
    Yang J.-L., Shen Z.-M., Han J.-X.
    A study on the biological characteristics of an established human gastric adenocarcinoma cell line (SGC-7901).
    Ke Xue Tong Bao 27:1355-1358(1982)

    PubMed=6443274
    Lin C.-H., Fu Z.-M., Liu Y.-L., Yang J.-L., Xu J.-F., Chen Q.-S., Chen H.-M.
    Investigation of SGC-7901 cell line established from human gastric carcinoma cells.
    Chin. Med. J. 97:831-834(1984)

    DOI=10.1007/978-4-431-68252-3_114
    Wang L.-B., Qian B.-W., Xia Y.-X.
    Establishment of human gastric cancer cell line (SGC-7901) intraperitoneally transplantable in nude mice.
    (In) Recent advances in management of digestive cancers; Toshio T. (eds.); pp.416-418; Springer; Tokyo (1993)

    DOI=10.1016/B978-0-12-333530-2.50014-9
    Sekiguchi M., Suzuki T.
    Gastric tumor cell lines.
    (In) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.287-316; Academic Press; New York (1994)

    PubMed=16038636; DOI=10.1111/j.1745-7254.2005.00149.x
    Tang X.-Q., Bi H., Feng J.-Q., Cao J.-G.
    Effect of curcumin on multidrug resistance in resistant human gastric carcinoma cell line SGC7901/VCR.
    Acta Pharmacol. Sin. 26:1009-1016(2005)

    PubMed=16525997; DOI=10.1002/pmic.200402031
    Yang Y.-X., Xiao Z.-Q., Chen Z.-C., Zhang G.-Y., Yi H., Zhang P.-F., Li J.-L., Zhu G.
    Proteome analysis of multidrug resistance in vincristine-resistant human gastric cancer cell line SGC7901/VCR.
    Proteomics 6:2009-2021(2006)

    DOI=10.11569/wcjd.v19.i12.1219
    Chen G., Wang Q.-R., Qiu H., Ke S.-D., Xiang Y., Hu S.-M.
    Relationship of cellular drug resistance to proportion of side population cells and expression of Mdr1 and ERCC1 in human gastric cell line SGC7901/OXA.
    Shi Jie Hua Ren Xiao Hua Za Zhi 19:1219-1224(2011)

    PubMed=22576950; DOI=10.1007/s13277-012-0406-3
    Xu Y.-Y., Mao X.-Y., Song Y.-X., Zhao F., Wang Z.-N., Zhang W.-X., Xu H.-M., Jin F.
    Midkine confers adriamycin resistance in human gastric cancer cells.
    Tumor Biol. 33:1543-1548(2012)

    PubMed=26116706; DOI=10.1096/fj.14-266718
    Ye F., Chen C.-G., Qin J., Liu J., Zheng C.-Y.
    Genetic profiling reveals an alarming rate of cross-contamination among human cell lines used in China.
    FASEB J. 29:4268-4272(2015)

    PubMed=27917905; DOI=10.1038/srep38376
    Chen Z.-Z., Li W.-M., Zhang Y., Yu M., Shan L.-F., Yuan D.-Z., Liu F.-R., Fang J.
    Establishment of a gastric cancer subline with high metastatic potential using a novel microfluidic system.
    Sci. Rep. 6:38376-38376(2016)

    PubMed=28498440; DOI=10.3892/ijo.2017.3983
    Zhuang K., Zhang L.-X., Zhang X., Tang H.-L., Zhang J., Yan Y., Han K., Guo H.-Q.
    Gastrin induces multidrug resistance via the degradation of p27Kip1 in the gastric carcinoma cell line SGC7901.
    Int. J. Oncol. 50:2091-2100(2017)

    PubMed=28851942; DOI=10.1038/s41598-017-09660-w
    Bian X.-C., Yang Z.-L., Feng H.-L., Sun H., Liu Y.-Q.
    A combination of species identification and STR profiling identifies cross-contaminated cells from 482 human tumor cell lines.
    Sci. Rep. 7:9774-9774(2017)

    PubMed=29717028; DOI=10.1042/BSR20180277
    Zhang Y.-Q., Yu S., Zhang Z.-Z., Zhao G., Xu J.
    Long non-coding RNA AK096174 promotes cell proliferation and invasion in gastric cancer by regulating WDR66 expression.
    Biosci. Rep. 38:BSR20180277.1-BSR20180277.12(2018)

    Cross-references
    Cell line databases/resourcesMCCL; MCC:0000418
    TOKU-E; 3764
    Anatomy/cell type resourcesBTO; BTO:0002392
    Cell line collections (Providers)CCTCC; GDC0150
    Chemistry resourcesChEMBL-Cells; CHEMBL3307739
    ChEMBL-Targets; CHEMBL614909
    PubChem_Cell_line; CVCL_0520
    Encyclopedic resourcesWikidata; Q54953170
    Experimental variables resourcesEFO; EFO_0006293
    Gene expression databasesGEO; GSM844685
    GEO; GSM1374869

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